Hermina Silonga-Arce
San Juan de Dios Hospital, PhilippinesPresentation Title:
Coincidental Finding of Sertoli-Leydig cell tumor in a postmenopausal woman with mild hyperandrogenism, ovarian teratoma, and pelvic organ prolapse: A case report
Abstract
A Sertoli-Leydig cell tumor (SLCT) is an
extremely rare type of sex cord stromal tumor of the ovary, which mainly
secretes testosterone, thus manifestations of hyperandrogenism commonly appear.
This paper shall discuss a case of a postmenopausal woman who presented with
pelvic organ prolapse, large left ovarian cyst and mild signs of
hyperandrogenism. She underwent total abdominal hysterectomy with bilateral
salpingo-oophorectomy, which on microscopic examination of the specimens,
revealed a Mature cystic teratoma on the left ovary and an incidental finding
of a well-differentiated SLCT, on the grossly normal-looking ovary. This
histopathologic diagnosis of SLCT explained the patient’s hyperandrogenic
characteristics. Authors likewise discussed the proper management of SLCT,
including immunostaining and need for adjuvant chemotherapy.
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