Sae Kyung Choi
The Catholic University of Korea, Republic of KoreaPresentation Title:
Perinatal outcomes in pregnancies complicated by maternal thrombocytopenia: A retrospective cohort study
Abstract
Maternal thrombocytopenia, affecting approximately 10% of pregnancies, may be physiological (e.g., gestational thrombocytopenia) or pathological (e.g., immune thrombocytopenic purpura, aplastic anemia, preeclampsia, systemic lupus erythematosus). While gestational thrombocytopenia is typically benign, its severity and etiology may impact maternal and neonatal outcomes. This study examined the association between thrombocytopenia during pregnancy and perinatal outcomes, focusing on maternal hemorrhage and neonatal thrombocytopenia.
Methods: A retrospective analysis was conducted of 182 pregnant women with thrombocytopenia who delivered at Incheon St. Mary’s Hospital and Seoul St. Mary’s Hospital between 2009 and 2019. Participants were classified A or B. Maternal hemorrhagic outcomes, transfusion needs, and neonatal platelet counts were evaluated. Statistical analyses were performed using univariate methods.
Results: Severe thrombocytopenia was associated with greater blood loss during delivery, incresead transfusion requirements and neonatal thrombocytopenia rates. Moderate to severe thrombocytopenia was more frequently identified in neonates delivered by mothers with immune thrombocytopenic purpura than in those delivered by mothers with gestational thrombocytopenia.
Conclusions: Both the severity and etiology of maternal thrombocytopenia significantly affect the risk of maternal hemorrhage and neonatal thrombocytopenia. Careful prenatal assessment is essential to optimize management and reduce complications.
Biography
Sae Kyung Choi received his PhD in Medicine from the College of Medicine, The Catholic University of Korea, in 2012. She is currently an Associate Professor in the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, at Incheon St. Mary’s Hospital, the Catholic University of Korea. Her clinical and research interests include perinatal medicine, fetal growth restriction, and pregnancy complications.
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